Current Challenges in the Management of Hypothyroidism- Hypothyroidism, like many chronic conditions, is associated with long-term morbidity that can be minimized
through careful management. Primary thyroid failure is a continuous progression from a relatively symptomfree stage into overt disease in which abnormal levels of
thyroid hormones are accompanied by troubling symptoms, cognitive impairment, and a heightened risk of cardiovascular morbidity. There is ongoing debate over
what constitutes “normal” levels of thyroid hormones. As a result, researchers are exploring the risks posed by subclinical, asymptomatic disease, with the goal of clarifying the indications for treatment.
through careful management. Primary thyroid failure is a continuous progression from a relatively symptomfree stage into overt disease in which abnormal levels of
thyroid hormones are accompanied by troubling symptoms, cognitive impairment, and a heightened risk of cardiovascular morbidity. There is ongoing debate over
what constitutes “normal” levels of thyroid hormones. As a result, researchers are exploring the risks posed by subclinical, asymptomatic disease, with the goal of clarifying the indications for treatment.
Define goals of thyroid hormone replacement therapy in individuals with hypothyroidism. Identify thyroid hormone replacement products, their individual potency, and safety of interchangeability among products. Describe barriers to achieving and maintaining adequate thyrotropin concentrations in individuals with hypothyroidism. Define strategies for optimizing the benefit:risk profile of thyroid hormone replacement therapy.
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