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C. Diff- Emerging Therapies and Recurrence Prevention

Clostridium difficile Infection: Emerging Therapies and Recurrence Prevention-Rates of CDI incidence, hospitalizations, and deaths have been increasing in recent years, suggesting that current management of this condition may be suboptimal.  Although much has been discovered regarding the role of gastrointestinal flora in the pathogenesis of CDI, the mechanisms of recurrent disease and poor outcomes remain elusive. Surveys of practice patterns suggest that healthcare professionals are unaware of or fail to utilize optimal methods for managing patients with CDI.  Given the recent updated guidelines for CDI, combined with several new agents emerging for this disease, it is important that healthcare professionals be aware of the most current research and recommendations for the management of CDI.
Describe the role of gastrointestinal flora in health and the mechanisms of recurrent Clostridium difficile infection (CDI). Identify patients at risk for recurrence and poor outcomes. Summarize recent evolutions in CDI treatment options. Use appropriate CDI diagnostic testing. Choose appropriate infection control methods and therapies to improve patient outcomes.
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